Before You Try SARMs: What the Data Says

SARMs, or Selective Androgen Receptor Modulators, were developed to replicate the muscle-stimulating effects of anabolic steroids — but with more selectivity and fewer side effects. Unlike traditional steroids, SARMs target androgen receptors primarily in muscle and bone, making them useful in research on muscle wasting and bone fragility. Outside of labs, SARMs have found their way into gym culture, often used by people chasing muscle gains as an alternative to steroids.While SARMs are still under active research, we remain committed to sharing up-to-date, evidence-backed information to help users understand their potential effects and make informed decisions.

What are SARMs?

SARMs are synthetic molecules built to activate androgen receptors in a selective way. Instead of hitting the whole body like steroids do, they focus mostly on muscle and bone tissue. This selectivity is what makes them cleaner on paper — fewer effects on the prostate, liver, or skin, depending on the compound. Originally developed for medical use, SARMs have shown promise in managing muscle wasting, osteoporosis, and even hormone imbalances.   Many products available online often lack full transparency regarding purity and dosage. At Biaxol, each compound is lab-tested to ensure accuracy and consistency – what’s on the label is exactly what you get.

What are the benefits of SARMs?

• Muscle growth over short cycles
• Easier fat loss in conjunction with training and diet
• Better recovery between workouts
• Mild endurance boosts in certain compounds
• Less water retention than traditional anabolic steroids

How to take SARMs?

• Start with a low dose and monitor for side effects
• Most cycles run between 6 to 12 weeks
• Post-cycle therapy is often used to restore hormone levels
• Bloodwork before and after the cycle is strongly advised
• Compounds are usually taken orally — no injection needed

What are the best SARMs?

SARMs vary by use — cutting vs. bulking — as well as by potency, side effects, and hormonal suppression.  Here’s a quick overview of the most commonly discussed ones:

Ibutamoren (MK-677)

Though not technically a SARM, MK-677 often mentioned alongside them due to similar effects. It boosts growth hormone levels and is popular for recovery, improved sleep, and long-term muscle retention. It also increases appetite via ghrelin activation in a manner that supports fat oxidation.

Testolone (RAD-140)

A strong, anabolic compound known for adding muscle size and strength. RAD-140 binds tightly to androgen receptors and tends to suppress natural testosterone early in the cycle. It delivers strong results, but often with noticeable side effects.

Ostarine (MK-2866)

One of the mildest SARMs, Ostarine is often used for lean bulks or for cutting cycles. It helps maintain muscle when calories drop, and is known for fewer and milder side effects.

Which SARMs are recommended for beginners?

New users typically start with milder compounds or those with more predictable outcomes. Here are a few that are often recommended for entry-level use:

• Ligandrol (LGD-4033): Reliable for lean mass gain with moderate suppression.
• Cardarine (GW-501516): Technically a PPAR agonist, not a SARM — improves endurance and fat metabolism.
• Stenabolic (SR9009): Also not a true SARM — supports metabolic activity and stamina output.

Ligandrol (LGD-4033)

Often seen as a starting point due to its manageable profile. It helps with lean muscle gain and is typically run solo for first cycles.

Cardarine (GW-501516)

Reported by users to support endurance and fat metabolism, though not approved for these uses. While not a SARM, it’s occasionally combined with SARMs in off-label regimens, as it does not act on androgen receptors.

Stenabolic (SR9009)

Another compound frequently paired with SARMs. It affects metabolic rhythm and may improve cardio output, especially during cutting phases.

Experts Opinion

“SARMs hold promise as a new class of function‑promoting anabolic therapies, with the ability to selectively enhance muscle and bone strength while minimizing effects on non‑target tissues.” -Published in the NIH/NLM (National Institutes of Health/National Library of Medicine)

Are SARMs really effective?

Effectiveness depends on the specific compound, how it's dosed, and the user's baseline. Compounds like RAD140 and LGD4033 have been studied in early-phase clinical trials, showing potential for increasing lean body mass and improving strength markers under controlled conditions. Outside of research, many users report noticeable physical improvements within a few weeks of consistent use. Because SARMs are not regulated as medications, product quality can vary across the market. At Biaxol, we mitigate this risk through rigorous third-party testing and strict quality control—ensuring you get what’s on the label, every time.

How long does it take to feel the effects of SARMs?

Many users start noticing strength changes within 10–14 days. By week 3 or 4, physical differences — like harder muscles or slightly better pumps — may become visible. For compounds like MK-677, some effects such as increased appetite, deeper sleep, or mild water retention can start as early as day 3 to 5.

Are SARMs safe?

Here’s what users and researchers have reported:

• Testosterone levels can drop mid-cycle
• HDL cholesterol usually drops; LDL can increase
• Some liver markers rise, depending on the compound
• Sleep, mood, and libido may change — not always positively
• Long-term safety data doesn’t yet exist

Most SARMs suppress endogenous testosterone production, which is why post-cycle support plays a key role in recovery. Without it, hormonal imbalances may take longer to correct. Another concern is product consistency – quality can vary significantly across sellers, and what’s on the label doesn’t always match what’s in the bottle. To support recovery after a cycle, we offer solutions like our Post-Cycle Therapy (PCT) formula, developed to help restore hormonal balance. Our Testosterone Booster is also available for those looking to support natural testosterone production during the rebound phase.

Are SARMs legal in the UK?

In the UK, SARMs are available for purchase as research compounds and are not classified as licensed medicines or dietary supplements. Their distribution falls under specific regulatory guidelines that govern how they can be marketed and sold.
At Biaxol, we operate with full awareness of these regulations. Our products are clearly labeled and intended for research-related purposes only. We’re committed to maintaining transparency, quality, and responsible presentation across our SARMs range.

Is it possible to fail a drug test for using SARMs?

Yes. SARMs show up on anti-doping tests. Even small traces can lead to disqualification in sports governed by WADA or similar bodies. Detection windows vary but can stretch weeks after the last dose, especially with longer half-life compounds.

Where to buy SARMs?

• Only purchase from vendors with third-party lab testing
• Avoid companies marketing SARMs as supplements or therapy
• Check legality in your location before ordering
• Look for transparent ingredient labels, though these are not always trustworthy
• Use caution — contamination and underdosing are common issues

Disclaimer: This article is for informational purposes only. SARMs are not approved for human use outside clinical research. Individuals should speak with a qualified medical professional before considering any form of hormonal intervention.



Sources:

1. https://pubmed.ncbi.nlm.nih.gov/32748554/
2. https://www.goodrx.com/well-being/movement-exercise/what-are-sarms
3. https://my.clevelandclinic.org/health/body/22804-ghrelin
4. https://onlinelibrary.wiley.com/doi/10.1111/cen.15135
5. https://www.uspharmacist.com/article/recreational-use-of-selective-androgen-receptor-modulators
6. https://www.sciencedirect.com/science/article/abs/pii/S0731708521005446