S23 is one of the strongest and most advanced SARMs, highly valued by experienced lifters and competitors due to its unparalleled hardening and shredding effects on muscles. This is your go-to compound in case you want to achieve a dry, dense, and competition-ready physique. We highlight S23 since it yields elite-level results, with proper cycle planning and PCT.
What is S23 SARM?
S23, a SARM developed by GTX, Inc., was part of early research into male hormonal contraceptives. Unlike the classical anabolic steroids, which act on multiple tissues and have many side effects, S23 binds selectively to androgen receptors in muscle and bone. These targeted activities enable the stimulation of muscle growth and fat loss with real potency.
What really differentiates S23, however, is its exceptionally high binding affinity, measured by a Ki value of 1.7 nM – in simple terms, this means it binds extremely tightly to androgen receptors and acts very efficiently to mimic testosterone’s anabolic effects. Because S23 is so potent, this SARM is used mostly by experienced athletes looking to get very lean, vascular, and super defined during either a cut or recomposition phase. It is known, though, to cause strong testosterone suppression, which makes post-cycle therapy extremely necessary.
S23 SARM Benefits
S23 displays strong, dose-dependent effects. Below are the key physiological outcomes observed and documented in research and athlete reports:
- Massive Lean Muscle Gain (Anabolic Effect): S23 promotes anabolic activity that supports noticeable increases in lean muscle mass and overall muscle density.
- Invasive Fat Loss: S23 is highly effective for reducing fat mass and thus a popular drug used during cutting or pre-contest phases.
- Enhanced Power & Strength: There are reports of users achieving spectacular gains in power and strength during the cycle.
- Muscle Hardening and Density: Due to its potent mechanism and complete agonist character, S23 is renowned for helping to cultivate a hard, dense, and defined muscular look.
- Increased Bone Mineral Density (BMD): In studies, S23 induced an increase in bone mineral density, which suggests an affirming effect on bone health.
S23 SARM Dosage
Because of its strong activity, dosing S23 correctly is essential for achieving results while minimizing hormonal suppression. It’s best suited for experienced users who already have a Post Cycle Therapy (PCT) plan ready to help restore natural balance afterward.
Below is how Biaxol S23 is packaged and what general usage suggestions are:
- Our bottle contains: 60 capsules of 10 mg
- Total amount of S23: 600 mg S23
- Recommended starting dose: 1 capsule per day (10 mg)
- Maximum dose suggested: Not more than 2 capsules daily (20 mg)
- 60-day supply: With 60 capsules, 1 capsule daily, you have a 60-day supply.
- Typical short cycle: 6–8 weeks, followed by necessary Post Cycle Therapy (PCT) due to its suppressive nature.
Warning: Since S23 is a full agonist and is a high suppressor of natural testosterone, a long PCT protocol is not optional after the cycle.
S23 SARM Ingredients
We like to keep things simple but powerful, and that’s exactly what’s inside Biaxol S23. No fillers, no fluff – just clean, effective ingredients that work in harmony to deliver real results. Each capsule combines precision and purity, designed to help your body push harder, recover faster, and look sharper. Here’s what makes the formula stand out:
- Principal Active Ingredient: S-23 (10 mg)
- It is the potent SARM that binds to the androgen receptors in order to trigger anabolic activity, strength increase, and fat loss.
- Secondary Ingredient: Black Pepper Fruit Extract (Piper nigrum) (5 mg)
- This compound is usually used to accompany supplements as a way to enhance the bioavailability and absorption of the active ingredient, bestowing it with its full capacity.
- Other Ingredients: Vegetable capsule (HPMC)
- We use a non-animal-derived capsule as the delivery vehicle.
We Also Recommend
To get the most from your S23 cycle while protecting your body, consider pairing it with these supportive supplements:
- TUDCA: Provides essential liver support during your SARM cycle.
- Cycle Support (ALA, GSE, CoQ10, Zinc, BPE): Helps maintain antioxidant balance and organ health.
- PCT Blend (Tribulus, DHEA, Maca, DIM): Assists in restoring natural testosterone levels after your cycle.
- Stacking Notes: Avoid combining S23 with other potent SARMs at the same time to minimize hormonal stress.
Tips for Safe Use:
- Follow a structured dosing schedule and PCT plan.
- Maintain proper nutrition, hydration, and recovery habits to support your gains.
S23 SARM with Other Supplements and Medication
S23 is a very strong compound. Stacking it with other medications is at one’s own risk and with extreme caution regarding possible interactions and hazards:
- Hormone-Affecting Drugs: If you are currently on hormone therapy, adding S23 may disrupt the Hypothalamic–Pituitary–Gonadal (HPG) axis, the body’s natural hormonal regulation system, due to S23’s strong suppressive effects.
- Medications for Chronic Conditions: If you are already on prescription medication for a chronic condition, you should definitely talk to your doctor first before getting on S23. Little is known about how S23 will mix with the metabolism or potency of these drugs.
- Supplements with Androgenic Activity: Stacking S23 with other chemicals that impact the Androgen Receptor (like other SARMs or Prohormones) is not generally suggested due to the potential to seriously increase the risk and severity of side effects, particularly HPG axis suppression as well as organ stress.
- Competitive Use Considerations: S23 is particularly banned by the World Anti-Doping Agency (WADA) and the NCAA. It is classified as a banned peptide hormone. Using it will lead to a positive drug test.
Never stack S23 with other medications or supplements without speaking with a professional.
S23 SARM Side Effects
Transparency is paramount, and as a powerful, non-FDA drug, S23 does have some serious potential side effects attached. Know awareness allows you to effectively manage risk.
The most frequently reported side effects and risks are:
- Heavy Testosterone Suppression: S23 has been reported to be heavily suppressive and causes a significant dose-dependent decrease in T, LH, and FSH levels. This suppression is the largest reason for needed PCT.
- Potential for Organ Damage: SARMs have been linked with serious adverse effects, such as elevated liver enzymes, heart attack, and stroke. Anecdotal case reports rarely mention kidney, liver, and prostate hypertrophy.
- Mood/Mental Health Changes: Related studies report that S23 is capable of producing changes in mechanisms involved in neurodegenerative and psychiatric disorders, such as those involved in depression.
- Hair Loss: Some users experience temporary hair loss as a result of the extreme androgenic signaling.
What Experts Say About S23 SARM
S23 is known by researchers and experienced athletes for its strong effects on hardening the muscles, fat reduction, and retaining lean mass. Researchers point out that human clinical data is limited, but the pathway behind this compound, selective androgen receptor binding, supports reported effects when used in properly structured cycles: increased muscle density, vascularity, and strength on cuts or recomposition phases.
Meanwhile, authorities remind users that S23 is unapproved and not regulated; its long-term safety profile is not known, and it must be used responsibly, carefully dosed, and followed by a well-planned PCT. As experts advise, users are balancing ambition for physique improvement with awareness of potential hormonal suppression and allowing recovery protocols to maximize benefits safely.
In other words, the results with S23 are possible for experienced athletes using structured cycles, but to achieve them while managing risks, informed and disciplined use is necessary.
Final Words
At Biaxol, we believe in transparency, safe usage, and informed decisions. If you choose to use S23, you should understand its strong suppressive effects and the importance of a comprehensive health-monitoring plan. Be mindful of your dosage, cycle length, and the possibility of unstudied side effects. The opportunity to achieve an impressive physique is real, but so are the risks if the compound is used without extreme caution.
