Melatonin is a neurohormone produced mainly by the pineal gland in the brain, and it is the one that is responsible, as mentioned above, for regulating the sleep-wake cycles, helping to reduce the time needed to fall asleep. The positive effect is obtained with an intake of at least 1mg of melatonin shortly before sleeping.
It is really effective in reducing the time it takes to fall asleep; The minimum dose to use is about 0.3mg 1-2 hours before going to sleep
Some of the activities that melatonin performs include normal cardiovascular function, sleep-wake timing, energy and blood sugar control, and a few other important functions that describe its effectiveness in reducing inflammatory stress.
Unlike other supplements currently on the market, this hybrid release product (quick release and extended release) helps mimic the body's natural sleeping pattern.
GABA or Gamma-aminobutyric acid is a non-protein amino acid that is widely present in microorganisms, plants and animals. It is the main inhibitory neurotransmitter in the mammalian central nervous system (CNS). which counteracts the effects of glutamate (an excitatory neurotransmitter), providing a sense of calm thanks to counteracting neurotransmitters with an excitatory effect.
L-Theanine is an amino acid that acts on GABA receptors, helping the brain enter a “calm state”, it also alters the levels of the neurotransmitters serotonin and dopamine.
L-Glycine is a vital amino acid that is beneficial to the body. It helps protect the gastrointestinal system, the neurological system, the musculoskeletal system and the body's metabolism from harmful factors that can cause the human body to malfunction. Glycine is even a neurotransmitter and can help increase glutathione in the brain by providing anti-inflammatory effects. Glycine provides a sweet flavor when consumed in the body. Although glycine plays a crucial role in the human body, the amino acid has received little to no attention until recently.
Despite having a massive impact on serotonin, glycine is known to be used as a therapeutic option for people to improve sleep quality as a novel and safe approach. Studies show that glycine can increase blood flow to the extremities by lowering the body's core temperature, which is an important signal for initiating sleep. When this happens, glycine can increase the time a person is in REM sleep, providing the person with a good night's sleep. Further research shows that glycine can inhibit orexin-stimulating neurons that are responsible for arousal and energy homeostasis, which is critical and can induce non-REM sleep or even nocturnal awakening,
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